Question: From that which is known is that the prayer of the woman inside her home is better than her praying in the masjid; So if she abandoned praying in al-Masjid al-Haraam (in Makkah) or al-Masjid an-Nabawee (in Madeenah) and (instead) prayed inside her home, would she be rewarded with the multiple reward for the prayer therein (as in al-Masjid al-Haraam and al-Masjid an-Nabawee)?
Answer: As regards Makkah, then the multiple (prayer) reward is attained in all of the Haram (sacred area). So if a woman prayed inside her home in Makkah, then she has attained the multiple (prayer) reward inshaa.-Allaah. As for Madeenah, then the multiple (prayer) reward is specific to al-Masjid an-Nabawee, however, if the woman prayed inside her home in Madeenah in accordance with the statement of the Messenger (sal-Allaahu `alayhe wa sallam) then much good is anticipated for her, and she will be rewarded for her sincere intention and her love for (wanting to) pray in the Masjid of the Messenger (sal-Allaahu `alayhe wa sallam). And Allaah is the Most knowledgeable.
[Shaykh Saailh ibn Fowzaan, al-Muntaqaa min Fataawa Shaykh Saalih al-Fowzaan – Volume 3, Page 300, Fatwa No.442]